[NP-ADMP1] Advanced Diploma in Medical and Pharmaceutical Technology (ADMP1)

Offered by School of Life Sciences & Chemical Technology

Advanced Diploma

About Course
Course Structure
Entry Requirements
Financial Matters
Course Schedule

About Course

Course Objectives

ADMP1 provides trained manpower for companies in the Biomedical manufacturing sector, particularly those involved in the manufacturing of pharmaceuticals, biopharmaceuticals, medical supplies and medical devices. It also equips students with skills and breadth of knowledge to enable them to find employment in other organizations where high levels of quality assurance and analytical services are required such as in the manufacturing and sales of analytical and scientific equipment and in analytical laboratories.

Course Description

The Advanced Diploma in Medical and Pharmaceutical Technology is a part-time CET course, consist of the following modules:
1. Cell & Molecular Biology (45 hrs)
2. Microbiology (36 hrs)
3. Pharmaceutical Microbiology (36 hrs)
4. Applied Genomics & Proteomics (36 hrs)
5. Mammalian Cell Culture (36 hrs)
6. Upstream Processing (36 hrs)
7. Downstream Processing (36 hrs)
8. Drug Formulation (45 hrs)
9. cGMP Compliance (36 hrs)
10. QC & Pharmaceutical Analytics (36 hrs)
11. Validation (36 hrs)
12. QA & Documentation (45 hrs)

Trainer's Profile

New Jen Yan

Dr New Jen Yan attained his Ph.D. from the Faculty of Medicine and his B.Sc. (Hons) in Microbiology from the National University of Singapore (NUS). He has a broad background in Biotechnology, Microbiology, Molecular Biology, and Immunology and serves as a Senior Lecturer at Ngee Ann Polytechnic. He is an ACTA-certified trainer and an advocate for lifelong learning.

Dr New has developed and taught modules on Immunology, Mammalian Cell Culture, Biotechnology for Biomedical Science (BMS) Diploma students at Ngee Ann Polytechnic, and Applied Genomics & Proteomics, QC Analytics, and Applied Microbiology for working adults attending the Advanced Diploma in Medical and Pharmaceutical Technology (ADMPT). Furthermore, he has designed the curricula and conducted customised training programmes for industry professionals from companies such as Thermo Fisher Scientific and Rentokil Singapore. Dr New’s outstanding contributions to education have been acknowledged with accolades such as the Staff Excellence Award and the Staff Teaching Award.

Dr New has also conducted research on using microalgae as a biofuel source and the alleviation of Graft-vs-Host disease in animal models. His post-doctorate work at the Department of Microbiology at NUS focused on developing a novel tuberculosis vaccine, further enhancing his research skills.

Dr New continues to mentor and educate the upcoming generation of biotechnologists and researchers, leveraging his extensive research experience and passion for teaching.


Geng Anli

Dr Geng Anli obtained her Ph. D in Chemical and Environmental Engineering from the National University of Singapore (NUS) under a government scholarship. She received her M. Eng and B. Eng degrees in Biochemical Engineering from Tianjin University, P. R. China

Dr Geng Anli is a Senior Lecturer at School of Life Sciences and Chemical Technology of Ngee Ann Polytechnic.  She is also the Cofounder and Director of Mycosortia Pte. Ltd. Prior to joining Ngee Ann Polytechnic, she worked at the Institute of Environmental Science and Engineering (IESE) as a Research Scientist and group leader.

Dr Geng has more than 20 years R&D experience, working extensively on environmental biotechnology, green energy technology and industrial biotechnology. She's an expert in fermentation, fermented food, and fiber bioconversion, and has received multi-million SGD research grants. Her current focus is environmental sustainability, waste valorisation and decarbonisation.

Dr. Geng’s work has been presented in numerous scientific journals and international conferences. She is currently the President of the BioEnergy Society of Singapore (BESS). She is also a member of SGS International Certification Services Singapore Pte Ltd - Impartiality Advisory Committee. She obtained Ngee Ann Polytechnic Teaching Award in 2006, Ngee Ann Polytechnic Staff Excellence Award - Technology Award in 2012, and Institution of Chemical Engineers (IChemE) Singapore Award on Sustainable Technology in 2012.

Dr. Geng is primarily teaching in Chemical & Biomolecular Engineering related courses. She has taught reaction engineering, transfer processes –   heat and mass, engineering mathematics, chemical engineering laboratories, QC & Phamaceutical Analysis, and Captone projects. She has taught fermentation engineering, fermentation technology practicals as a part-time lecturer for Beijing Union University. She is now developing adult learning courses on sustainability and decarbonisation.


Huang Yinyi

Huang Yinyi received her PhD in Biological Sci from the National University of Singapore.

Yinyi’s areas of expertise are in Biosafety and Risk Management and Cell Culture

Prior to joining Ngee Ann Polytechnic as a Lecturer, Yinyi was a Junior Research Fellow at Temasek Life Sciences Laboratory and then a Visiting Scientist. She was a Research Fellow at The Mechanobiology Institute and later joined JN Medsys as a Senior Scientist.

Having more than a decade of teaching experience with Ngee Ann Polytechnic, Xinyi teaches the “Advanced Diploma in Medical & Pharmaceutical Technology” programme to adult learners in the CET space.

Neviliappan Shanmugam

Neviliappan Shanmugam holds a Ph. D (Life Sciences) from the National University of Singapore. He earned his B. Ed from the Dept of Education, Annamalai University. Neviliappan also holds a M. Sc (Zoology) from Annamalai University and an B. Sc (Zoology) from Arumugam Pillai Seethai Ammal Arts College, Madurai Kamaraj University. He is an ACTA certified Adult Educator (Institute of Adult Learning, Singapore).

Neviliappan has developed two short courses on Basic Statistical Methods & Data Presentation and Applied Biostatistics for the CET learners. These are two days short courses.

Neviliappan currently teaches Applied Biostatistics and Science modules in the PET and the CET spaces. He has been the Programme Manager for the “Specialist Diploma in Bioinformatics & Analytics (SDBIA)” since 2019. He is also module leader for the module, “Biomedical and Healthcare Data Sciences”.

Neviliappan is a service learning (S-L) specialist representing the School of Life Sciences & Chemical Technology.

Neviliappan and his Final year project students have published a scientific paper in Aquaculture Asia Pacific journal Nov/Dec 2023 issue pages 39-41, Aqua Culture Asia Pacific (aquaasiapac.com). He has worked as a Co-Chair in World Aquaculture Society (WAS), Singapore in Dec 2022 and presented a paper in this conference.

Course Structure

TPG course reference No.

TGS-2022014231

Advanced Diploma in Medical & Pharmaceutical Technology

Post-Diploma Certificate in Biopharmaceutical Manufacturing
Downstream Processing (NP-013221)
The module will cover the purification of recombinant proteins. Topics will include large scale cell separation and affinity, ion exchange and gel filtration chromatography. Issues relating to the packing of columns and the selection of column packings will also be covered.
Drug Formulation (NP-013222)
This module focuses on the design and formulation of two-phase pharmaceutical products, including suspensions, emulsions and solid pharmaceutical products, particularly as they relate to the formation sterile drugs. Topics include drug formulations, processing of sterile drug formulations, preparation of pharmaceuticals, specialised dosage forms, GMP and Validation.
Mammalian Cell Culture (NP-013219)
This module equips students with strong aseptic techniques and an understanding of the application of cell cultures in biopharmaceutical production and research and development. Topics include types of sterilisation methods, preparation of media and maintenance of cell cultures.
Upstream Processing (NP-013220)
The module will provide an overview of the processes involved in producing biopharmaceuticals from raw materials. The module will cover cells as biocatalysts, applications of recombinant technology, cell banking, bioreactors, bioreactor operation and factors involved in the scale up of animal cell cultures from flask to reactor. Issues relating to end product accumulation and the quantitation of cell growth will also be covered. Practical sessions will include the methods of enumerating cell populations and the operation of laboratory scale bioreactors.
Post-Diploma Certificate in Molecular & Microbiological Analyses
Applied Genomics & Proteomics (NP-013213)
This module provides a deeper understanding into the various analytical tools from protein purification, analysis, quantitation to contaminant detection. Participants will receive hands-on training on the design of experiments to extract and purify proteins from cells, apply tools in the analysis and study of proteins, interpret data and appreciate the applications of genomics in the industrial and medical field. Students will also study the function of genes and their interaction within a genome, the human genome project, bioinformatics and gene therapy.
Cell & Molecular Biology (NP-013211)
This module provides an introduction to basic cell & molecular biology concepts. It equips students with an understanding of cell biology, including structure and function of cells and its organelles, cellular transport mechanisms, cell divisions, DNA replication, central dogma of biology, basic genetic principles, and cell development.
Microbiology (NP-013212)
Lectures will cover the scope of microbiology including the types, classification and properties of bacteria, fungi and viruses. The laboratory sessions will equip students with essential skills in microbiology including aseptic technique, staining methods and methods for enumeration, culturing, maintenance and identification of microorganisms.
Pharmaceutical Microbiology (NP-013214)
The module will cover standard methods in pharmaceutical microbiology including microbiological testing of non-sterile and sterile products, preservative testing, sterilization techniques, validation of the sterilization process, environmental monitoring and viral testing and clearance. The module will also provide an overview of microorganisms typically encountered or tested for as contaminants in pharmaceutical and biopharmaceutical manufacturing.
Post-Diploma Certificate in Pharmaceutical Quality Systems
QA & Documentation (NP-013218)
The module will cover documentation and its role in Quality Assurance in pharmaceutical manufacturing. Documentation requirements under GMP, ISO Quality Management System and ICH guidelines will be compared. International quality and regulatory requirements including those of the HSA will be compared. The module will cover documentation requirements for quality events including customer complaints, Out of Specifications, Deviation Investigations, Root Cause Analysis and Corrective Action Preventative Action. The topic of documentation requirements for Qualification and Validation will cover Change Control, IQ, OQ and PQ, method validation for incoming materials, process control and finished product quality. The components of the QA Documentation System and Good Documentation Practice will be covered. The module will also cover Quality Audits, regulatory inspections and interpreting and responding to FDA 483 Warning Letters.
QC & Pharmaceutical Analytics (NP-013216)
This module studies analytical techniques used for the detection, identification and quantitative determination of drugs and related substances. Techniques for the evaluation of analytical data and validation of analytical methods will be introduced as well as an overview of QC issues and regulatory requirements related to the quality of biopharmaceuticals.
Validation (NP-013217)
The module will cover the principles and practices of Validation providing an introduction to organization of the validation process. Topics will include validation of critical utilities, cleaning and sterilization, methods, computer systems and processes. The validation of biopharmaceutical processes will also be covered.
cGMP Compliance (NP-013215)
The module will provide an overview of the GXP regulatory standards and requirements in pharmaceutical industry and starting with the drug development process to the production of the finished product. GMPs and the Quality Management Systems covering organization and personal, equipment and facilities, contamination control, documentation management, packaging and labeling and API and biologics manufacturing will be covered.

Entry Requirements

Condition 1

Highest qualification

Local Polytechnic Diploma/ Degree in technical disciplines such as Science, Engineering or Information Technology.
and

Highest qualification

-
or

Condition 2

Highest qualification

Local Polytechnic Diploma or Degree in a non-engineering / non-technology disciplines.
and

Highest qualification

A Credit or a minimum grade of C6 in GCE “O” level Science Subject.

Financial matters

Course fees payable (incl. GST & excl. supplementary fee)

Description Post-Diploma Certificate in Molecular & Microbiological Analyses Post-Diploma Certificate in Pharmaceutical Quality Systems Post-Diploma Certificate in Biopharmaceutical Manufacturing Total course fee
Full Course fee $3,802.36 $3,802.36 $3,802.36 $11,407.08
Singapore Citizen Aged 40 & Above $380.24 $380.24 $380.24 $1,140.72
PR Sponsored by SME $395.93 $395.93 $395.93 $1,187.79
Singapore Citizen Sponsored by SME $395.93 $395.93 $395.93 $1,187.79
Singapore Citizen Aged Below 40 $570.35 $570.35 $570.35 $1,711.05
Singapore PR $1,520.94 $1,520.94 $1,520.94 $4,562.82
Long-Term Visit Pass Plus $3,802.36 $3,802.36 $3,802.36 $11,407.08

GST rate

The course fees payable above are inclusive of 9% GST rate.

Payment option

The first payment needs to be made after accepting the offer.

Allowed payment by

Post-Secondary Education Account (Adhoc withdrawal form);Post-Secondary Education Account (Standing order form);SkillsFuture Credits (SFC);Credit card (e-payment);Debit card (e-payment);PayNow (e-payment)

Refund and withdrawal policy

  • Please note that a 100% refund will be available if the withdrawal request is submitted more than or equal to 14 days before the course start date.
  • Please note that a 50% refund will be available if the withdrawal request is submitted less than 14 days before the course start date.
  • Please note that no refund will be available if the withdrawal request is submitted on or after the course start date.

Course 
Schedule

Class Day(s): Mon- - Fri (3 to 4 evenings per week)
Time: 6:30pm to 10:30pm
Delivery mode: Face-to-face & Home-based Learning (Async & Sync)